SCHEMBL7005961

SCHEMBL7005961

O=C1C2CC3(O)CC1CC(C(=O)O)(C2)C3

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.34
PKM P14618 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
EPHX2 P34913 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5407456 0.87 EPHX2 (0.34) HSD11B1PKML3MBTL1EPHX2
SCHEMBL5409968 0.80 EPHX2 (0.33) PKMEPHX2
SCHEMBL24274069 0.78 ABL1 (0.36) HSD11B1L3MBTL1EPHX2CNR2
SCHEMBL6999213 0.78
SCHEMBL8581404 0.71
SCHEMBL8581708 0.71
SCHEMBL8584647 0.71
SCHEMBL28845132 0.71 HSD11B1 (0.56) HSD11B1PKML3MBTL1CNR2
SCHEMBL16593601 0.71 HSD11B1 (0.56) HSD11B1PKML3MBTL1CNR2
SCHEMBL18799647 0.71 HSD11B1 (0.56) HSD11B1PKML3MBTL1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2024-07-18 US disclosed
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2024-07-18 US disclosed
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2024-07-18 US disclosed
WO-2021262426-A9 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2022-03-17 WO disclosed
WO-2021262426-A9 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2022-03-17 WO disclosed
WO-2021262426-A2 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2021-12-30 WO disclosed
WO-2021262426-A2 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION ARISAN THERAPEUTICS INC. (US) 2021-12-30 WO disclosed
EP-1081150-B1 4-Oxatricyclo(4.3.1.1-3,8)undecan-5-one derivatives and process for producing the same DAICEL CHEM (JP) 2003-10-29 EP disclosed
US-6486330-B1 4-oxatricyclo[4.3.1.1 3,8]undecan-5-one derivative and process for producing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-26 US disclosed
EP-1081150-A1 4-Oxatricyclo(4.3.1.1-3,8)undecan-5-one derivatives and process for producing the same Daicel Chemical Industries, Ltd. (JP) 2001-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238265-A1 ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION IFNAR1, NR4A3, NR0B2 HSD11B1 2165/4885PKM 4800/4885L3MBTL1 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.