Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ASPH | Q12797 | 2/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543099 | 0.79 | KEAP1 (0.40) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL10515953 | 0.79 | KEAP1 (0.42) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL7006447 | 0.79 | KEAP1 (0.38) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL7008840 | 0.78 | CA2 (0.42) | KEAP1NFE2L2KDM4ETSHRHSD17B10 | |
| SCHEMBL19478153 | 0.77 | DRD4 (0.34) | — | |
| SCHEMBL8056962 | 0.75 | KEAP1 (0.42) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL31034649 | 0.75 | KEAP1 (0.42) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL23496686 | 0.74 | KEAP1 (0.47) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL2670263 | 0.74 | KEAP1 (0.39) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL21358502 | 0.72 | AKR1C2 (0.44) | KEAP1NFE2L2KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |