Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ASPH | Q12797 | 2/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578094 | 0.82 | GABRP (0.40) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL7006318 | 0.79 | KEAP1 (0.37) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL7006447 | 0.79 | KEAP1 (0.38) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL522378 | 0.78 | SLC6A4 (0.38) | KDM4E | |
| Fluoride SCHEMBL28471027 | 0.76 | KEAP1 (0.47) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL503374 | 0.76 | KEAP1 (0.47) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| Fluoride SCHEMBL6445071 | 0.76 | KEAP1 (0.47) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL29816825 | 0.76 | KEAP1 (0.47) | KEAP1NFE2L2KDM4EASPHKDM8 | |
| SCHEMBL16850337 | 0.76 | CES2 (0.42) | KEAP1KDM4EASPHKDM8PRKAB2 | |
| SCHEMBL10455376 | 0.74 | KEAP1 (0.45) | KEAP1NFE2L2KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415742-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND AND CATALYST THEREFOR | Sumitomo Chemical Company, Limited (JP) | 2012-02-08 | — | — | EP | disclosed |