Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836915 | 0.85 | L3MBTL3 (0.31) | — | |
| SCHEMBL9927928 | 0.70 | KDM2B (0.38) | PIM1 | |
| SCHEMBL12568609 | 0.70 | KDM2B (0.38) | PIM1 | |
| SCHEMBL12568610 | 0.68 | KDM2B (0.37) | PIM1 | |
| SCHEMBL9927914 | 0.68 | KDM2B (0.37) | PIM1 | |
| SCHEMBL2380225 | 0.68 | ALDH1A1 (0.43) | — | |
| SCHEMBL10639937 | 0.65 | — | — | |
| SCHEMBL29904650 | 0.65 | L3MBTL3 (0.34) | PIM1 | |
| SCHEMBL2378470 | 0.65 | CA12 (0.33) | — | |
| SCHEMBL24721280 | 0.63 | SIGMAR1 (0.42) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | claimed |