Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7237888 | 1.00 | MTNR1A (0.59) | MTNR1AMTNR1BMAPTADRA1AKDM1A | |
| SCHEMBL7010711 | 0.83 | MTNR1A (0.51) | MTNR1AMTNR1BMAPTADRA1AKDM1A | |
| SCHEMBL7011236 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1BMAPTADRA1AKDM1A | |
| SCHEMBL7238438 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1BMAPTADRA1AKDM1A | |
| SCHEMBL7235756 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BMAPTKDM1AMAOA | |
| SCHEMBL7235758 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BMAPTKDM1AMAOA | |
| SCHEMBL7094962 | 0.78 | MAPT (0.56) | MTNR1AMTNR1BMAPTADRA1AKMT2A | |
| Ammonia Solution, Strong SCHEMBL27509223 | 0.77 | MAPT (0.55) | MTNR1AMTNR1BMAPTADRA1AKMT2A | |
| SCHEMBL6906698 | 0.76 | KDM1A (0.56) | ADRA1AKDM1AMAOA | |
| SCHEMBL7009286 | 0.75 | MTNR1A (1.00) | MTNR1AMTNR1BKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |