Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235756 | 1.00 | MTNR1A (0.54) | MTNR1AMTNR1BMAPTKMT2AHPGD | |
| SCHEMBL7228935 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BTP53 | |
| SCHEMBL7228928 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BTP53 | |
| SCHEMBL7006460 | 0.79 | MTNR1A (0.59) | MTNR1AMTNR1BMAPTKMT2AHPGD | |
| SCHEMBL7237888 | 0.79 | MTNR1A (0.59) | MTNR1AMTNR1BMAPTKMT2AHPGD | |
| SCHEMBL7094962 | 0.73 | MAPT (0.56) | MTNR1AMTNR1BMAPTKMT2AHPGD | |
| Ammonia Solution, Strong SCHEMBL27509223 | 0.72 | MAPT (0.55) | MTNR1AMTNR1BMAPTKMT2AHPGD | |
| SCHEMBL7010711 | 0.72 | MTNR1A (0.51) | MTNR1AMTNR1BMAPTKMT2AHPGD | |
| SCHEMBL7004821 | 0.70 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL7007379 | 0.70 | MTNR1A (0.65) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |