Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 12/20 | 1.00 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230881 | 1.00 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHSD17B1HSD17B2 | |
| SCHEMBL7010965 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL7230327 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL7010173 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7228835 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7009286 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL7238295 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL7012333 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CSMN1; SMN2NPSR1 | |
| SCHEMBL7094759 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CSMN1; SMN2NPSR1 | |
| SCHEMBL7011236 | 0.76 | MTNR1A (0.61) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216856-C | Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same | ADIR (FR) | 2005-08-31 | — | — | CN | claimed |
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | claimed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | claimed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | claimed |
| CN-1250771-A | Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same | ADIR (FR) | 2000-04-19 | — | — | CN | claimed |
| CN-1216856-C | Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same | ADIR (FR) | 2005-08-31 | — | — | CN | disclosed |
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |
| CN-1250771-A | Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same | ADIR (FR) | 2000-04-19 | — | — | CN | disclosed |