SCHEMBL7010965

SCHEMBL7010965

CCC(=O)NC1CC1c1c(OC)ccc2ccc(OC)cc12

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 14/20 0.77
MTNR1B P49286 12/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7230327 1.00 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL7228835 0.92 MTNR1A (0.76) MTNR1AMTNR1B
SCHEMBL7010173 0.92 MTNR1A (0.76) MTNR1AMTNR1B
SCHEMBL7006478 0.87 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7230881 0.87 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7237873 0.86 MTNR1A (0.76) MTNR1AMTNR1B
SCHEMBL7009066 0.86 MTNR1A (0.76) MTNR1AMTNR1B
SCHEMBL7231439 0.82 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL7011682 0.82 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL7013039 0.80 MTNR1A (0.53) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1216856-C Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same ADIR (FR) 2005-08-31 CN claimed
US-6583319-B1 Treating or preventing melatoninergic disorders LES LABORATOIRES SERVIER (FR) 2003-06-24 US claimed
EP-0994102-B1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-03-19 EP claimed
EP-0994102-A1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2000-04-19 EP claimed
CN-1250771-A Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same ADIR (FR) 2000-04-19 CN claimed
CN-1216856-C Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same ADIR (FR) 2005-08-31 CN disclosed
US-6583319-B1 Treating or preventing melatoninergic disorders LES LABORATOIRES SERVIER (FR) 2003-06-24 US disclosed
EP-0994102-B1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-03-19 EP disclosed
EP-0994102-A1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2000-04-19 EP disclosed
CN-1250771-A Novel cyclocompound having cycloalkylene chain, prepn. method and pharmaceutical compositions contg. same ADIR (FR) 2000-04-19 CN disclosed