Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605146 | 0.88 | CES2 (0.50) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL10347642 | 0.84 | AKT1 (0.61) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL22231498 | 0.82 | KDM4E (0.44) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL24970184 | 0.80 | ALDH1A1 (0.49) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL14692510 | 0.80 | CYP11B1 (0.45) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL293634 | 0.80 | CES2 (0.60) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL29952517 | 0.80 | CES2 (0.60) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| Acrylic Acid SCHEMBL27852823 | 0.79 | ALDH1A1 (0.76) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL9113114 | 0.78 | CES2 (0.58) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL7829063 | 0.78 | CES2 (0.58) | CES2CES1ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945820-A | Method for synthesizing alpha, beta-unsaturated aldehyde compound by copper catalysis | 江苏海洋大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-113444032-B | Carbazole oxime ester compound, preparation method, composition and application | 优禘股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-20220296592-A1 | BROMODOMAIN INHIBITORS TO TARGET THERAPY-RESISTANT CANCER | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2022-09-22 | — | — | US | disclosed |
| CN-113444032-A | Carbazole oxime ester compound, preparation method, composition and application | 优禘股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020229225-A1 | PROCESS FOR THE PREPARATION OF DIHALOBENZOPHENONES, NEW CHEMICALS USEFUL FOR ITS IMPLEMENTATION AND METHODS FOR PREPARING SAID CHEMICALS | RHODIA OPERATIONS (FR) | 2020-11-19 | — | — | WO | disclosed |
| EP-3736260-A1 | PROCESS FOR THE PREPARATION OF DIHALOBENZOPHENONES, NEW CHEMICALS USEFUL FOR ITS IMPLEMENTATION AND METHODS FOR PREPARING SAID CHEMICALS | Rhodia Operations (FR) | 2020-11-11 | — | — | EP | disclosed |
| CN-106995368-A | A kind of non ATP competitiveness FGFR1 inhibitor and its application | 温州医科大学 | 2017-08-01 | — | — | CN | disclosed |
| WO-2015200680-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-30 | — | — | WO | disclosed |
| US-8513258-B2 | Cinnamoyl-piperazine derivatives and their use as par-1 antagonists | PIERRE FABRE MEDICAMENT (FR) | 2013-08-20 | — | — | US | disclosed |
| US-20120232097-A1 | CINNAMOYL-PIPERAZINE DERIVATIVES AND THEIR USE AS PAR-1 ANTAGONISTS | PEREZ MICHEL (FR) | 2012-09-13 | — | — | US | disclosed |
| EP-1309551-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014273-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232097-A1 | CINNAMOYL-PIPERAZINE DERIVATIVES AND THEIR USE AS PAR-1 ANTAGONISTS | F2R, F2RL1, F2RL3 | CES2 471/4885CES1 206/4885ALDH1A1 1137/4885 |
| US-20220296592-A1 | BROMODOMAIN INHIBITORS TO TARGET THERAPY-RESISTANT CANCER | BRD1, SMARCE1, SMARCA1 | CES2 2019/4885CES1 2452/4885ALDH1A1 2472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.