Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006942 | 1.00 | HRH2 (0.52) | HRH2HRH1MBTD1L3MBTL3EPHX2 | |
| Trifluoroacetic Acid SCHEMBL7718799 | 0.92 | GPR6 (0.51) | HRH2HRH1MBTD1L3MBTL3EPHX2 | |
| Trifluoroacetic Acid SCHEMBL7718796 | 0.92 | GPR6 (0.51) | HRH2HRH1MBTD1L3MBTL3EPHX2 | |
| SCHEMBL16627285 | 0.78 | L3MBTL3 (0.60) | MBTD1L3MBTL3EPHX2PDK1PDK2 | |
| SCHEMBL31387922 | 0.77 | HPGD (0.68) | EPHX2GPR183PDK1PDK2PDK3 | |
| SCHEMBL31387924 | 0.77 | HPGD (0.68) | EPHX2GPR183PDK1PDK2PDK3 | |
| SCHEMBL11439644 | 0.77 | DPP4 (0.66) | HRH2HRH1ALDH1A1DPP4L3MBTL1 | |
| SCHEMBL21552116 | 0.77 | DPP4 (0.66) | HRH2HRH1ALDH1A1DPP4L3MBTL1 | |
| SCHEMBL3633068 | 0.76 | HPGD (0.71) | EPHX2GPR183PDK1PDK2PDK3 | |
| SCHEMBL13088810 | 0.75 | GRM5 (0.51) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991650-B1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER IND & SANTE (FR) | 2003-09-10 | — | — | EP | disclosed |
| EP-0991650-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000387-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-01-07 | — | — | WO | disclosed |