Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515837 | 0.88 | TAAR1 (0.54) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL7931860 | 0.88 | TAAR1 (0.42) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL21382605 | 0.88 | L3MBTL1 (0.42) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL2172552 | 0.85 | TAAR1 (0.44) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL6542154 | 0.80 | TAAR1 (0.46) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL11108664 | 0.80 | TAAR1 (0.47) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL8417751 | 0.78 | TAAR1 (0.45) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL16898703 | 0.78 | TAAR1 (0.61) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL1680408 | 0.78 | TAAR1 (0.45) | TAAR1HTR2AIDO1MAOAMAOB | |
| SCHEMBL4670222 | 0.78 | MEN1 (0.46) | TAAR1HTR2AIDO1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627433-B1 | PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE | EISAI CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5700938-A | Intermediates for imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5608068-A | Process for the preparation of imidazopyridine derivatives and intermediates | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5557002-A | Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists | EISAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |