Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | MMP13 | P45452 | 5/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010800 | 0.87 | MMP1 (0.68) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7015826 | 0.83 | MMP9 (0.79) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7010378 | 0.82 | MMP13 (0.77) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7006635 | 0.75 | MMP13 (0.78) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7012284 | 0.71 | MMP1 (0.84) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7010014 | 0.71 | MMP9 (1.00) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7009011 | 0.70 | MMP1 (0.70) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7008346 | 0.69 | MMP13 (0.78) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7009676 | 0.69 | MMP1 (1.00) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7011776 | 0.68 | MMP1 (0.46) | MMP1MMP9MMP13ADAM17NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021413-B1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO BICYCLIC HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | WYETH CORP (US) | 2003-06-11 | — | — | EP | claimed |