SCHEMBL70074

SCHEMBL70074

ClOc1cccc(OCl)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2A6 P11509 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
ALDH1A1 P00352 2/20 0.31
RHEB Q15382 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
PNMT P11086 1/20 0.31
DPP4 P27487 1/20 0.30
LMNA P02545 3/20 0.30
IDO1 P14902 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL691908 0.82 TSHR (0.52) TSHRCA12CA1CA2CA4
SCHEMBL3790244 0.73 CA1 (0.58) TSHRCA12CA1CA2CA4
SCHEMBL10935253 0.73
SCHEMBL23487743 0.71 TLR8 (0.41) TSHRCYP1A2CYP2A6ALDH1A1PNMT
Phosphine SCHEMBL27403110 0.71 TSHR (0.47) TSHRALDH1A1DPP4LMNASMN1; SMN2
SCHEMBL10611186 0.69 ALDH1A1 (0.58) TSHRCA12CA1CA2CA4
SCHEMBL3784828 0.69 KCNH2 (0.43) CA12CA1CA2CA4CA7
SCHEMBL11360852 0.67 MAPT (0.50) CYP1A2CYP2A6ALDH1A1CYP3A4CYP2D6
SCHEMBL19612269 0.67 MCHR1 (0.44) CA1CA2CA7CA9ALDH1A1
SCHEMBL6437406 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-1009729-B1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING & MFG (US) 2005-01-19 EP disclosed
CN-1125030-C Halogenated acrylates and polymers made therefrom MINNESOTA MINING & MFG (US) 2003-10-22 CN disclosed
US-6362379-B2 ACRYLATES HAVING HIGH DEGREE OF HALOGENATION AND POLYMERS USING THESE MONOMERS; USEFUL FOR OPTICAL WAVEGUIDES AND TELECOMMUNICATION 3M INNOVATIVE PROPERTIES COMPANY 2002-03-26 US disclosed
US-6313245-B1 USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES 3M INNOVATIVE PROPERTIES COMPANY 2001-11-06 US disclosed
US-20010037028-A1 Halogenated acrylates and polymers derived therefrom 3M INNOVATIVE PROPERTIES COMPANY 2001-11-01 US disclosed
US-6288266-B1 HALOGENATED ACRYLATES OR THIOACRYLATES FOR POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-09-11 US disclosed
CN-1259932-A Halogenated acrylates and polymers derived therefrom MINNESOTA MINING & MFG (US) 2000-07-12 CN disclosed
EP-1009729-A1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-06-21 EP disclosed
US-6005137-A POLYMERS USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-12-21 US disclosed
WO-1998056749-A1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-17 WO disclosed
US-5115074-A Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers TEIJIN LIMITED (JP) 1992-05-19 US disclosed
EP-0431891-A1 Epoxy compounds, production processes thereof and cured product of the epoxy compound TEIJIN LIMITED (JP) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TSHR 3263/4885CYP1A2 2262/4885CYP2A6 1560/4885
US-20010037028-A1 Halogenated acrylates and polymers derived therefrom ZYX, ACR, ORMDL3 TSHR 1965/4885CYP1A2 2983/4885CYP2A6 2487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.