SCHEMBL691908

SCHEMBL691908

Oc1cccc(OCl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 4/20 0.43
LMNA P02545 4/20 0.43
ALOX15 P16050 4/20 0.43
HSD17B10 Q99714 4/20 0.43
MAPT P10636 4/20 0.43
HPGD P15428 3/20 0.43
CYP3A4 P08684 3/20 0.43
TP53 P04637 2/20 0.43
MAPK1 P28482 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ALOX12 P18054 1/20 0.43
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.39
EGFR P00533 2/20 0.38
FYN P06241 2/20 0.38
MMP9 P14780 2/20 0.38
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ADAMTS4 O75173 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9454007 0.83 TSHR (0.54) TSHRALDH1A1LMNAALOX15HSD17B10
SCHEMBL70074 0.82 TSHR (0.32) TSHRALDH1A1LMNACYP3A4CA2
SCHEMBL10611186 0.80 ALDH1A1 (0.58) TSHRALDH1A1LMNAALOX15HSD17B10
SCHEMBL1008486 0.79 TP53 (0.64) TSHRALDH1A1LMNAALOX15HSD17B10
SCHEMBL70607 0.78 CYP3A4 (0.50) TSHRALDH1A1LMNAALOX15HSD17B10
SCHEMBL1125159 0.77 TSHR (0.48) TSHRALDH1A1LMNAALOX15HSD17B10
SCHEMBL1931496 0.77
SCHEMBL30020007 0.77
SCHEMBL69881 0.76
SCHEMBL28061476 0.76 TSHR (0.64) TSHRALDH1A1LMNAALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111960932-B Dichlororesorcinol compound and preparation method and medical application thereof 沈阳药科大学 2022-11-08 CN claimed
CN-111960932-A Dichlororesorcinol compound and preparation method and medical application thereof 沈阳药科大学 2020-11-20 CN claimed
CN-103736239-A Fire extinguishing composition containing aldoketones compound XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-04-23 CN claimed
CN-103736237-A Fire extinguishing composition containing hydroxyketone compound and derivatives of hydroxyketone compound XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-04-23 CN claimed
EP-1161414-B1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2003-10-01 EP claimed
US-20020055648-A1 Cyanate esters having flame resistant properties JPMORGAN CHASE BANK, N.A. 2002-05-09 US claimed
EP-1161414-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES Vantico AG (CH) 2001-12-12 EP claimed
US-6242638-B1 FIREPROOFING USING CURED MIXTURES VANTICO INC. 2001-06-05 US claimed
WO-2000055123-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2000-09-21 WO claimed
US-20240167922-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD KYOTO UNIVERSITY (JP) 2024-05-23 US disclosed
EP-4306927-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD Kyoto University (JP) 2024-01-17 EP disclosed
CN-111960932-B Dichlororesorcinol compound and preparation method and medical application thereof 沈阳药科大学 2022-11-08 CN disclosed
CN-111960932-B Dichlororesorcinol compound and preparation method and medical application thereof 沈阳药科大学 2022-11-08 CN disclosed
CN-111960932-B Dichlororesorcinol compound and preparation method and medical application thereof 沈阳药科大学 2022-11-08 CN disclosed
WO-2000055123-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2000-09-21 WO disclosed
US-5115074-A Condensation of carboxylic aldehyde and phenol as a novolak for heat, chemical, water resistant polymers TEIJIN LIMITED (JP) 1992-05-19 US disclosed
EP-0431891-A1 Epoxy compounds, production processes thereof and cured product of the epoxy compound TEIJIN LIMITED (JP) 1991-06-12 EP disclosed
EP-0387554-A2 Liquid epoxy polymer composition and use thereof International Business Machines Corporation (US) 1990-09-19 EP disclosed
EP-0375980-A2 Epoxy composition of increased thermal conductivity and use thereof International Business Machines Corporation (US) 1990-07-04 EP disclosed
US-4416950-A COATING WITH A DICYCLOPENTENYL ACRYLATE MONOMER AND POLYMERIZING ANDREWS PAPER & CHEMICAL CO. (US) 1983-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055648-A1 Cyanate esters having flame resistant properties PCCA, FABP4, MCCC2 TSHR 4633/4885ALDH1A1 1536/4885LMNA 112/4885
US-20240167922-A1 TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD TST, TTR, ALB TSHR 2764/4885ALDH1A1 3942/4885LMNA 1853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.