Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | SCN1A | P35498 | 3/20 | 0.60 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.60 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898705 | 1.00 | ALDH1A1 (0.60) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL25166782 | 1.00 | ALDH1A1 (0.60) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL6792141 | 0.99 | SCN1A (0.61) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL7899203 | 0.99 | KMT2A (0.61) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL7523378 | 0.95 | NPY5R (0.55) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL12720636 | 0.94 | KMT2A (0.63) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL3540913 | 0.94 | KMT2A (0.66) | ALDH1A1KMT2AMEN1NPY5RCYP19A1 | |
| SCHEMBL8342506 | 0.93 | KMT2A (0.56) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL31284709 | 0.93 | KMT2A (0.68) | ALDH1A1KMT2AMEN1NPY5RCYP19A1 | |
| SCHEMBL8342508 | 0.92 | KMT2A (0.57) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225007-A1 | Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases | APOTEX INC. | 2003-12-04 | — | — | US | disclosed |
| EP-1348710-A1 | Sulfonamide derivatives of 3-substituted imidazo[1,2-D]-1,2,4-thiadiazoles and 3-substituted-[1,2,4]thiadiazolo[4,5-A]benzimidazole as inhibitors of fibrin cross-linking and transglutaminases | Apotex Inc. (CA) | 2003-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225007-A1 | Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases | PIGS, FGB, SERPINE1 | ALDH1A1 689/4885CYP3A4 746/4885SCN1A 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.