Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 5/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006211 | 0.86 | THRA (0.32) | THRATHRBESR1 | |
| SCHEMBL7006238 | 0.81 | THRB (0.31) | THRATHRB | |
| SCHEMBL7010259 | 0.80 | ESR1 (0.39) | FFAR4THRATHRBESR1 | |
| SCHEMBL7592050 | 0.73 | THRA (0.36) | THRATHRB | |
| SCHEMBL7006368 | 0.72 | PTGS1 (0.32) | — | |
| SCHEMBL5234729 | 0.72 | THRB (0.36) | FFAR4THRATHRBESR1KDM4E | |
| SCHEMBL7003687 | 0.69 | ESR1 (0.37) | THRBESR1RXRA | |
| SCHEMBL5235017 | 0.69 | THRA (0.34) | THRATHRBKDM4E | |
| SCHEMBL7562047 | 0.68 | TNF (0.37) | ESR1 | |
| SCHEMBL5234473 | 0.68 | THRB (0.37) | THRATHRBESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062764-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-15 | — | — | WO | disclosed |