SCHEMBL700791

SCHEMBL700791

O=C1CC(C2CCCCC2)C(=O)O1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16237581 0.98 ALDH1A1 (0.30) MAPT
SCHEMBL11863377 0.93
SCHEMBL12110858 0.89 KDM4E (0.31)
SCHEMBL11981737 0.89 KDM4E (0.31)
SCHEMBL114258 0.83 TSHR (0.35)
SCHEMBL15786373 0.83 TSHR (0.35)
SCHEMBL18537682 0.83 TSHR (0.35)
SCHEMBL15780501 0.83 TSHR (0.35)
SCHEMBL18807102 0.83 TSHR (0.35)
SCHEMBL11485502 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111420068-B Polyethylene glycol-dendritic polylysine/anhydride-cisplatin compound and preparation method and application thereof 浙江大学 2021-11-09 CN claimed
CN-111420068-A Polyethylene glycol-dendritic polylysine/anhydride-cisplatin compound and preparation method and application thereof 浙江大学 2020-07-17 CN claimed
CN-110755639-A Polyethylene glycol-dendritic polylysine/anhydride-cisplatin compound and preparation method and application thereof 浙江大学 2020-02-07 CN claimed
CN-111420068-B Polyethylene glycol-dendritic polylysine/anhydride-cisplatin compound and preparation method and application thereof 浙江大学 2021-11-09 CN disclosed
CN-111420068-A Polyethylene glycol-dendritic polylysine/anhydride-cisplatin compound and preparation method and application thereof 浙江大学 2020-07-17 CN disclosed
CN-110755639-A Polyethylene glycol-dendritic polylysine/anhydride-cisplatin compound and preparation method and application thereof 浙江大学 2020-02-07 CN disclosed
EP-2997046-B1 CELLULOSE ETHERS ESTERIFIED WITH DICARBOXYLIC ACIDS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-25 EP disclosed
US-9890221-B2 Cellulose ethers esterified with dicarboxylic acid DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-13 US disclosed
CN-105164162-B The cellulose ether being esterified with dicarboxylic acids 陶氏环球技术有限责任公司 2017-11-28 CN disclosed
US-20160289344-A1 CELLULOSE ETHERS ESTERIFIED WITH DICARBOXYLIC ACID REGENTS OF THE UNIVERSITY OF MINNESOTA 2016-10-06 US disclosed
US-9376413-B1 Succinic anhydrides from epoxides CORNELL UNIVERSITY (US) 2016-06-28 US disclosed
EP-1599496-A2 HEPATITIS C INHIBITOR PEPTIDE ANALOGS Boehringer Ingelheim International GmbH (DE) 2005-11-30 EP disclosed
US-6908901-B2 Hepatitis C inhibitor peptide analogs BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) 2005-06-21 US disclosed
WO-2004101602-A2 HEPATITIS C INHIBITOR PEPTIDE ANALOGS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-11-25 WO disclosed
US-20040224900-A1 Hepatitis C inhibitor peptide analogs BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-11-11 US disclosed
US-20040224900-A1 Hepatitis C inhibitor peptide analogs BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-11-11 US disclosed
US-20040224900-A1 Hepatitis C inhibitor peptide analogs BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-11-11 US disclosed
US-6228986-B1 REDUCTIVE ALKYLATION OF ALPHA-NITROGEN OF RESIN-BOUND PROTECTED LYSINE, ACYLATION WITH PROTECTED-AMINO ACID, DEBLOCKING, ACYLATING WITH SUBSTITUTED SUCCINIC ANHYDRIDE, REMOVING PROTECTION FROM LYSINE, THEN CYCLIZATION ORTHO-MCNEIL PHARMACEUTICAL, INC. 2001-05-08 US disclosed
US-4725373-A CORROSION RESISTANCE FOR METAL TOOLS AND EQUIPMENT USED IN OIL AND GAS WELLS THE DOW CHEMICAL COMPANY (US) 1988-02-16 US disclosed
US-3960937-A REACTION PRODUCT OF PETROLEUM SULFONIC ACIDS, POLYAMINES, CYCLIC ANHYDRIDES PHILLIPS PETROLEUM COMPANY (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040224900-A1 Hepatitis C inhibitor peptide analogs RNASE1, HAVCR2, CTRL MAPT 4574/4885CHRM2 4877/4885CHRM1 4777/4885
US-20160289344-A1 CELLULOSE ETHERS ESTERIFIED WITH DICARBOXYLIC ACID SCO2, SUCNR1, MCCC2 MAPT 1794/4885CHRM2 6/4885CHRM1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.