Methylene Chloride

Methylene Chloride

SCHEMBL700799

CC(Cl)Cl.ClCCl

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL7463180 1.00 ALDH1A1 (0.67)
1,2-Dichloroethane SCHEMBL28875111 0.84 TSHR (0.60)
1,2-Dichloroethane SCHEMBL36872 0.84
Ethyl Chloride SCHEMBL11811185 0.84
Methylene Chloride SCHEMBL29210337 0.83 ALDH1A1 (0.46)
Trichloroethane SCHEMBL28756506 0.83 TSHR (0.46)
SCHEMBL5438089 0.82
SCHEMBL5728116 0.82
SCHEMBL126 0.82
SCHEMBL11523834 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453872-B1 COPOLYMERS AS DEWAXING ADDITIVES EVONIK OIL ADDITIVES GMBH (DE) 2016-04-13 EP claimed
EP-2630143-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF Apotex Pharmachem Inc. (CA) 2013-08-28 EP claimed
WO-2012051692-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC. (CA) 2012-04-26 WO claimed
US-20110034465-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC. (CA) 2011-02-10 US claimed
EP-0098012-A2 Process for preparing (o-hydroxyaryl)-methanols BLASCHIM S.p.A. (IT) 1984-01-11 EP claimed
US-20240199579-A1 PROCESS FOR PREPARING A COT INHIBITOR COMPOUND GILEAD SCIENCES, INC. 2024-06-20 US disclosed
US-11845737-B2 Process for preparing a Cot inhibitor compound GILEAD SCIENCES, INC. (US) 2023-12-19 US disclosed
EP-4126862-A1 PROCESS FOR PREPARING A COT INHIBITOR COMPOUND GILEAD SCIENCES, INC. (US) 2023-02-08 EP disclosed
US-20220411374-A1 ALTERNATE PROCESSES FOR THE PREPARATION OF OMECAMTIV MECARBIL DR. REDDY'S LABORATORIES LIMITED (IN) 2022-12-29 US disclosed
CN-115052857-A Compound (I) 住友化学株式会社 2022-09-13 CN disclosed
CN-113372383-B Preparation method of organic phosphate compound 中南大学 2022-08-02 CN disclosed
WO-2021202688-A1 PROCESS FOR PREPARING A COT INHIBITOR COMPOUND GILEAD SCIENCES, INC. (US) 2021-10-07 WO disclosed
EP-0058840-A1 Electron donor compounds and photoconductive charge transport materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-09-01 EP disclosed
EP-0054031-A1 SOLVENT DEWAXING PROCESS TEXACO DEVELOPMENT CORPORATION (US) 1982-06-23 EP disclosed
EP-0044214-A2 Novel phosphorous esters of cyanohydrins, pesticidal compositions including same, and methods of controlling pests using same UNION CARBIDE CORPORATION (US) 1982-01-20 EP disclosed
WO-1982000029-A1 SOLVENT DEWAXING PROCESS PITMAN H 1982-01-07 WO disclosed
US-4127598-A ADSORPTION WITH A MOLECULAR SIEVE OR CHARCOAL MCENTEE HARRY R 1978-11-28 US disclosed
US-4111790-A DILUTION CHILLING DEWAXING SOLVENT EXXON RESEARCH & ENGINEERING CO. (US) 1978-09-05 US disclosed
US-4042567-A S-Triazine prepolymers and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-4017488-A Process for preparing 7β-acylamino-7α-alkoxycephalosporins SANKYO COMPANY LIMITED (JA) 1977-04-12 US disclosed