Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 9/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.38 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480759 | 0.93 | TOP1 (0.46) | KMT2ATOP2ATOP2BTOP1GSK3B | |
| SCHEMBL7012357 | 0.93 | TOP1 (0.46) | KMT2ATOP2ATOP2BTOP1GSK3B | |
| SCHEMBL7011812 | 0.90 | KCNH2 (0.47) | CYP3A4CYP2C9KMT2ATOP2ATOP2B | |
| SCHEMBL7007324 | 0.85 | STAT3 (0.42) | CYP3A4CYP2C9KMT2ATOP2ATOP1 | |
| SCHEMBL7013177 | 0.84 | LMNA (0.50) | CYP3A4CYP2C9KMT2ATOP2ATOP2B | |
| SCHEMBL7014564 | 0.84 | CYP3A4 (0.46) | CYP3A4CYP2C9KMT2ATOP2ATOP2B | |
| SCHEMBL7006724 | 0.83 | KCNH2 (0.51) | KMT2ATOP2ATOP2BTOP1GSK3B | |
| SCHEMBL8478990 | 0.83 | KCNH2 (0.51) | KMT2ATOP2ATOP2BTOP1GSK3B | |
| SCHEMBL7010194 | 0.79 | CACNA1F (0.51) | CYP3A4CYP2C9KMT2ATOP2ATOP2B | |
| SCHEMBL6576258 | 0.78 | CYP3A4 (0.46) | CYP3A4CYP2C9KMT2ATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787720-B1 | PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KK (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-5910498-A | NOVEL COMPOUNDS HAVING REDUCED CYTOTOXICITY, PHOTOTOXICITY; TREATING BACTERIAL AND VIRAL INFECTIONS | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0787720-A1 | NOVEL PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-06 | — | — | EP | disclosed |