Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014319 | 0.94 | LMNA (0.63) | LMNAMEN1KMT2ACAPN1ALDH1A1 | |
| SCHEMBL7008289 | 0.86 | ALDH1A1 (0.50) | LMNAMEN1KMT2ACAPN1ALDH1A1 | |
| SCHEMBL7007055 | 0.84 | LMNA (0.54) | LMNAMEN1KMT2ACAPN1ALDH1A1 | |
| SCHEMBL10518008 | 0.83 | LMNA (0.58) | LMNAMEN1KMT2ACAPN1ALDH1A1 | |
| SCHEMBL7012905 | 0.83 | LMNA (0.45) | LMNAMEN1KMT2ACAPN1ALDH1A1 | |
| SCHEMBL7010887 | 0.83 | TOP2A (0.56) | LMNAMEN1KMT2ACAPN1ALDH1A1 | |
| SCHEMBL7007921 | 0.82 | DRD3 (0.60) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7010024 | 0.82 | ALDH1A1 (0.60) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7009203 | 0.82 | TOP2A (0.48) | LMNAMEN1KMT2ACAPN1ALDH1A1 | |
| SCHEMBL7007516 | 0.81 | KDM4E (0.52) | LMNAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |