Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007921 | 0.92 | DRD3 (0.60) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL7008949 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL7011168 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL7007516 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL7014319 | 0.83 | LMNA (0.63) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL7012437 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL8327077 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL7008090 | 0.82 | LMNA (0.55) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL7011144 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4EDRD3HPGDMEN1 | |
| SCHEMBL7007055 | 0.81 | LMNA (0.54) | ALDH1A1KDM4EDRD3HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |