Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720788 | 0.89 | CYP1A2 (0.56) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL7011867 | 0.87 | KMT2A (0.50) | EDNRBEDNRAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9196695 | 0.86 | LMNA (0.45) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL7009598 | 0.85 | ALDH1A1 (0.46) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL7013058 | 0.84 | LMNA (0.50) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL10435627 | 0.83 | ALDH1A1 (0.53) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL10387994 | 0.82 | EDNRB (0.51) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL9686670 | 0.79 | SMN1; SMN2 (0.41) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL9194034 | 0.79 | LMNA (0.56) | EDNRBEDNRACYP1A2ALDH1A1LMNA | |
| SCHEMBL423189 | 0.77 | LMNA (0.52) | EDNRBEDNRACYP1A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353640-B2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-0353640-B1 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0353640-A2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | Hoechst Schering AgrEvo GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |