Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008162 | 0.79 | EDNRB (0.48) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL7013058 | 0.77 | LMNA (0.50) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL423189 | 0.77 | LMNA (0.52) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL10435627 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL7009598 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL16404828 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL9542988 | 0.70 | SMN1; SMN2 (0.51) | SMN1; SMN2EDNRBEDNRAALDH1A1HTT | |
| Propane SCHEMBL10922188 | 0.70 | LMNA (0.42) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL10387994 | 0.69 | EDNRB (0.51) | SMN1; SMN2HIF1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL9739732 | 0.69 | CYP1A2 (0.50) | SMN1; SMN2HIF1AALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484750-A1 | Substituted sulfonylaminotriazolylpyrimidines | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |