SCHEMBL7008174

SCHEMBL7008174

Cc1ccc(S(=O)(=O)OC(C)N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA9 Q16790 3/20 0.48
CA12 O43570 2/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
GBA1 P04062 1/20 0.47
GAA P10253 2/20 0.46
VDR P11473 1/20 0.42
TLR9 Q9NR96 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 4/20 0.40
F2 P00734 2/20 0.40
PRSS1 P07477 2/20 0.40
PRSS2 P07478 2/20 0.40
PRSS3 P35030 2/20 0.40
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5557903 0.85 GAA (0.52) CA1CA2CA9CA12CA3
SCHEMBL2342945 0.85 GAA (0.52) CA1CA2CA9CA12CA3
SCHEMBL890642 0.83 GAA (0.50) CA1CA2CA9CA12CA3
SCHEMBL143705 0.83 GAA (0.50) CA1CA2CA9CA12CA3
SCHEMBL4671544 0.82 GBA1 (0.42) CA1CA2CA9CA12CA3
SCHEMBL2555662 0.82 GAA (0.48) CA1CA2CA9CA12CA3
SCHEMBL19949926 0.82 GAA (0.48) CA1CA2CA9CA12CA3
SCHEMBL6880747 0.82 CA12 (0.43) CA1CA2CA9CA12CA3
SCHEMBL1629581 0.82 TLR9 (0.48) CA1CA2CA9CA12CA3
SCHEMBL14778368 0.82 TLR9 (0.48) CA1CA2CA9CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015345-A1 ROUTE FOR CONSTRUCTING CHIRAL FRAGMENT OF FEZOLINETANT, INTERMEDIATE THEREOF, AND PREPARATION METHOD THEREFOR SHENZHEN HWAGEN PHARMACEUTICAL CO., LTD. (CN) 2026-01-15 US claimed
CN-118878478-A Route for constructing non-zolpidem chiral fragment, intermediate and preparation method thereof 深圳市华先医药科技有限公司 2024-11-01 CN claimed
US-12559484-B2 Route for constructing chiral fragment of fezolinetant, intermediate thereof, and preparation method therefor SHENZHEN HWAGEN PHARMACEUTICAL CO., LTD. (CN) 2026-02-24 US disclosed
US-20260015345-A1 ROUTE FOR CONSTRUCTING CHIRAL FRAGMENT OF FEZOLINETANT, INTERMEDIATE THEREOF, AND PREPARATION METHOD THEREFOR SHENZHEN HWAGEN PHARMACEUTICAL CO., LTD. (CN) 2026-01-15 US disclosed
CN-118878478-A Route for constructing non-zolpidem chiral fragment, intermediate and preparation method thereof 深圳市华先医药科技有限公司 2024-11-01 CN disclosed
CN-109206417-B Opioid receptor agonists and uses thereof 四川海思科制药有限公司 2023-01-03 CN disclosed
CN-115124520-A Opioid receptor agonists and uses thereof 四川海思科制药有限公司 2022-09-30 CN disclosed
EP-3938045-A1 SALTS OF A ISOCHROMANYL COMPOUND AND CRYSTALLINE FORMS, PROCESSES FOR PREPARING, THERAPEUTIC USES, AND PHARMACEUTICAL COMPOSITIONS THEREOF Sunovion Pharmaceuticals Inc. (US) 2022-01-19 EP disclosed
WO-2020186165-A1 SALTS OF A ISOCHROMANYL COMPOUND AND CRYSTALLINE FORMS, PROCESSES FOR PREPARING, THERAPEUTIC USES, AND PHARMACEUTICAL COMPOSITIONS THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2020-09-17 WO disclosed
EP-0285671-B1 PYRIDINE DERIVATIVES ASAHI CHEMICAL IND (JP) 2003-09-03 EP disclosed
EP-1261592-A1 ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2002-12-04 EP disclosed
US-5653970-A CLEANING COMPOUNDS; COSMETICS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-08-05 US disclosed
US-5641480-A ENHANCED STABILITY AND/OR VISCOSITY, CLARITY LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-06-24 US disclosed
US-5624906-A Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-04-29 US disclosed
US-5599587-A Phosphoric acid esters and their use in the preparation of biocompatible surfaces BIOCOMPATIBLES LIMITED (GB) 1997-02-04 US disclosed
US-5521293-A Heteroatom containing alkyl aldonamide compounds as superior foaming, more soluble nonionic surfactants and a process for their manufacture LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-05-28 US disclosed
EP-0556216-A1 PHOSPHORIC ACID ESTERS AND THEIR USE IN THE PREPARATION OF BIOCOMPATIBLE SURFACES. BIOCOMPATIBLES LTD (GB) 1993-08-25 EP disclosed
US-5126448-A Anxiolytic agents, learning enhancement ASAHI KASEI KOGYO K.K. (JP) 1992-06-30 US disclosed
WO-1992007858-A1 PHOSPHORIC ACID ESTERS AND THEIR USE IN THE PREPARATION OF BIOCOMPATIBLE SURFACES BIOCOMPATIBLES LIMITED (GB) 1992-05-14 WO disclosed
EP-0285671-A1 PYRIDINE DERIVATIVES Asahi Kasei Kabushiki Kaisha (JP) 1988-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015345-A1 ROUTE FOR CONSTRUCTING CHIRAL FRAGMENT OF FEZOLINETANT, INTERMEDIATE THEREOF, AND PREPARATION METHOD THEREFOR CYP19A1, CYP4F11, CYP11B1 CA1 746/4885CA2 934/4885CA9 1586/4885
US-12559484-B2 Route for constructing chiral fragment of fezolinetant, intermediate thereof, and preparation method therefor PTGIS, TMEM109, CYP11B1 CA1 1250/4885CA2 1025/4885CA9 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.