Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533995 | 0.93 | ESR1 (0.47) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL21628044 | 0.85 | HDAC4 (0.38) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL9714781 | 0.81 | ADRB1 (0.53) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL11241615 | 0.80 | ADRB1 (0.52) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| Resorcinol SCHEMBL27922774 | 0.79 | ALDH1A1 (0.57) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL14105185 | 0.78 | ADRB1 (0.50) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL13628507 | 0.78 | ADRB1 (0.48) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL9870224 | 0.78 | ACP3 (0.44) | TSHRGAAALDH1A1ACHETP53 | |
| SCHEMBL31490296 | 0.78 | ACP3 (0.44) | TSHRGAAALDH1A1ACHETP53 | |
| SCHEMBL11742505 | 0.77 | HSD17B10 (0.45) | HIF1ATSHRCYP3A4HSD17B10ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63063634-A | — | — | None | — | — | JP | disclosed |
| JP-63063634-A | — | — | None | — | — | JP | disclosed |
| CN-103764140-B | Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases | 韩国化学研究院 | 2017-05-17 | — | — | CN | disclosed |
| CN-103748060-B | 1,3-dioxo indene derivative, its pharmacy acceptable salt or optical isomer, its preparation method and comprise its pharmaceutical composition as antiviral activity composition | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-04-13 | — | — | CN | disclosed |
| CN-104981452-A | Skin whitening agent containing novel cyclic compound | RNS CO LTD | 2015-10-14 | — | — | CN | disclosed |
| CN-103764140-A | Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases | KOREA RES INST CHEM TECH | 2014-04-30 | — | — | CN | disclosed |
| CN-1115334-C | Pyridine derivative and medicine containing the same | OTSUKA PHARMA CO LTD (JP) | 2003-07-23 | — | — | CN | disclosed |
| EP-1267874-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | Aventis Pharma Deutschland GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| WO-2001066098-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | AVENTIS PHARMA DEUTSCHLAND GMBH | 2001-09-13 | — | — | WO | disclosed |
| US-5028615-A | Treatment of hypersensitivity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-07-02 | — | — | US | disclosed |
| EP-0395697-A4 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1991-03-13 | — | — | EP | disclosed |
| EP-0397697-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4?. | RORER INT OVERSEAS (US) | 1990-11-22 | — | — | EP | disclosed |
| EP-0395697-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4 | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1990-11-07 | — | — | EP | disclosed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| WO-1989004303-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |
| WO-1989004304-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |
| JP-S6363634-A | PRODUCTION OF 2-(3-HYDROXYPHENYL)PROPIONALDEHYDE | MARUZEN PETROCHEM CO LTD | 1988-03-22 | — | — | JP | disclosed |
| JP-S6363634-A | PRODUCTION OF 2-(3-HYDROXYPHENYL)PROPIONALDEHYDE | MARUZEN PETROCHEM CO LTD | 1988-03-22 | — | — | JP | disclosed |