Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651096 | 0.79 | ADRB1 (0.48) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL1723875 | 0.78 | ESR1 (0.44) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL7192764 | 0.78 | ADRB1 (0.52) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL1701121 | 0.78 | ADRB1 (0.43) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL12648355 | 0.78 | ADRB1 (0.52) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL7008264 | 0.78 | ADRB1 (0.52) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL11279836 | 0.78 | CES2 (0.51) | — | |
| SCHEMBL8591942 | 0.78 | ALDH1A1 (0.45) | SLC6A3ALDH1A1CYP3A4 | |
| SCHEMBL1712223 | 0.78 | ACP3 (0.47) | ADRB1LMNAADRB3TSHRMEN1 | |
| SCHEMBL13585083 | 0.78 | TYR (0.48) | ADRB1ADRA1AMIFHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |
| US-7456195-B2 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |