Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005285 | 0.86 | MAPT (0.37) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL7009750 | 0.79 | PKM (0.58) | ALDH1A1KDM4EPKMHTTPOLB | |
| SCHEMBL7007303 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1KDM4EPKM | |
| SCHEMBL7010043 | 0.76 | LMNA (0.43) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL7011507 | 0.75 | MAPT (0.38) | ALDH1A1KMT2AMEN1KDM4EPKM | |
| SCHEMBL29784708 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL28817121 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL12108929 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1KDM4EHTT | |
| SCHEMBL3190037 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KDM4EHTT | |
| SCHEMBL10391659 | 0.73 | MAPT (0.37) | ALDH1A1KMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6136823-A | BACTERICIDES OR VIRICIDES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0945435-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |