Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005289 | 0.85 | KMT2A (0.38) | ALDH1A1PKMMAPTLMNAKDM4E | |
| SCHEMBL7009944 | 0.77 | PKM (0.38) | ALDH1A1PKMMAPTLMNAGAA | |
| SCHEMBL6184304 | 0.76 | HSD17B2 (0.40) | ALDH1A1MAPTHSD17B2LMNAKDM4E | |
| SCHEMBL4671917 | 0.75 | MAPT (0.37) | ALDH1A1PKMMAPTLMNAKDM4E | |
| SCHEMBL7500869 | 0.73 | HSD17B2 (0.47) | ALDH1A1MAPTHSD17B2LMNAKDM4E | |
| SCHEMBL7007314 | 0.72 | KMT2A (0.40) | ALDH1A1PKMMAPTLMNAKDM4E | |
| SCHEMBL3189052 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1MAPTLMNAKMT2APOLB | |
| SCHEMBL7811252 | 0.72 | FBP1 (0.38) | ALDH1A1PKMMAPTLMNAGAA | |
| SCHEMBL27176878 | 0.72 | NPC1 (0.49) | ALDH1A1PKMMAPTHSD17B2LMNA | |
| SCHEMBL7004775 | 0.71 | POLB (0.36) | ALDH1A1MAPTLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6136823-A | BACTERICIDES OR VIRICIDES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0945435-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |