Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660360 | 0.87 | POLB (0.53) | POLBNR4A1NR4A2NR4A3NSD2 | |
| SCHEMBL11584658 | 0.84 | KDM4E (0.46) | POLBNSD2SIRT1CDC25BCA12 | |
| SCHEMBL8639079 | 0.84 | POLB (0.57) | POLBNSD2SIRT1IDO1PKM | |
| SCHEMBL942508 | 0.84 | SIRT1 (0.58) | POLBNR4A1NR4A2NR4A3NSD2 | |
| SCHEMBL29435080 | 0.84 | SIRT1 (0.58) | POLBNR4A1NR4A2NR4A3NSD2 | |
| SCHEMBL11669341 | 0.81 | SIRT1 (0.46) | POLBNSD2ACMSDSIRT1CDC25B | |
| SCHEMBL11669736 | 0.80 | SIRT1 (0.42) | POLBNSD2SIRT1CA12CA1 | |
| SCHEMBL429972 | 0.80 | POLB (0.54) | POLBNR4A1NR4A2NR4A3SIRT1 | |
| SCHEMBL29568923 | 0.80 | POLB (0.54) | POLBNR4A1NR4A2NR4A3SIRT1 | |
| SCHEMBL11670175 | 0.79 | ALDH1A1 (0.43) | POLBNSD2SIRT1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105321-A1 | Substituted with sulfonamide, sulfonate, or thiosulfonate groups of given formula; Use as a colorant and a pigment precursor, especially in light-sensitive compositions for color filters | WOLLEB ANNEMARIE (CH) | 2003-06-05 | — | — | US | disclosed |
| EP-1119590-B1 | SUBSTITUTED PHTHALOCYANINE | CIBA SC HOLDING AG (CH) | 2003-01-08 | — | — | EP | disclosed |
| US-6444807-B1 | PHOTOSENSITIVITY; COLOR FILTERS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-03 | — | — | US | disclosed |