Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660360 | 0.96 | POLB (0.53) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL231042 | 0.84 | SIRT1 (0.71) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL7008991 | 0.84 | POLB (0.43) | POLBSIRT1NSD2CA12CA1 | |
| SCHEMBL11472530 | 0.83 | PTPRG (0.58) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL234760 | 0.83 | RHEB (0.52) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL29888792 | 0.82 | POLB (0.74) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL1482567 | 0.82 | POLB (0.74) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL6935437 | 0.81 | SIRT1 (0.58) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL2024004 | 0.81 | ALDH1A1 (0.59) | POLBSIRT1KDM4EALDH1A1TDP1 | |
| SCHEMBL1447741 | 0.81 | KDM4E (0.59) | POLBSIRT1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799267-B1 | NAPHTALENEDICARBOXYLIC ACID POLYMERS CONTAINING ARYL THIOETHERS AND HAVING REDUCED FLUORESCENCE | EASTMAN CHEM CO (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0799267-A1 | NAPHTALENEDICARBOXYLIC ACID POLYMERS CONTAINING ARYL THIOETHERS AND HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5554720-A | Naphthalenedicarboxylic acid polymers containing aryl thioethers and having reduced fluorescene | EASTMAN CHEMICAL COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| WO-1996019517-A1 | NAPHTALENEDICARBOXYLIC ACID POLYMERS CONTAINING ARYL THIOETHERS AND HAVING REDUCED FLUORESCENCE | EASTMAN CHEMICAL COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |