SCHEMBL700914

SCHEMBL700914

CC(NC(=O)CBr)NS(=O)(=O)c1ccc(-c2ncc(-c3ccc(N(C)C)cc3)o2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.51
MMP9 P14780 4/20 0.51
HTR6 P50406 1/20 0.43
NPC1 O15118 3/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MMP3 P08254 1/20 0.36
ADRB2 P07550 2/20 0.35
ADRB1 P08588 2/20 0.35
ADRB3 P13945 2/20 0.35
HDAC1 Q13547 1/20 0.35
ADAMTS4 O75173 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
TP53 P04637 2/20 0.34
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34
RAB9A P51151 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300386 0.82 HTR6 (0.44) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014504 0.80 MMP2 (0.50) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014434 0.79 MMP9 (0.54) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014538 0.79 MMP2 (0.48) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014355 0.77 MMP9 (0.48) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014530 0.75 HTR6 (0.49) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014500 0.75 MMP2 (0.43) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014725 0.74 CA1 (0.50) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL6014405 0.74 HTR6 (0.48) MMP2MMP9HTR6NPC1ALOX15
SCHEMBL20356911 0.73 CA1 (0.49) MMP2MMP9HTR6NPC1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7851593-B2 Binding proteins as biosensors BECTON, DICKINSON AND COMPANY (US) 2010-12-14 US claimed
WO-2005080988-A1 BINDING PROTEINS AS BIOSENSORS BECTON, DICKINSON AND COMPANY (US) 2005-09-01 WO claimed
US-20050014290-A1 Binding proteins as biosensors BECTON, DICKINSON AND COMPANY 2005-01-20 US claimed
US-12487180-B2 Device and methods for quantifying analytes introduction Life Technologies Corporation (US) 2025-12-02 US disclosed
US-20250120620-A1 SYSTEMS AND METHODS FOR ANALYTE DETECTION Adaptyx Biosciences, Inc. 2025-04-17 US disclosed
US-20250025078-A1 ELECTRODE ARRANGEMENT WearOptimo Pty Ltd (AU) 2025-01-23 US disclosed
US-12109019-B2 Systems and methods for analyte detection Adaptyx Biosciences, Inc. (US) 2024-10-08 US disclosed
US-20240197213-A1 SYSTEMS AND METHODS FOR ANALYTE DETECTION Adaptyx Biosciences, Inc. 2024-06-20 US disclosed
WO-2024130117-A1 SYSTEMS AND METHODS FOR ANALYTE DETECTION Adaptyx Biosciences, Inc. (US) 2024-06-20 WO disclosed
US-20230384227-A1 DEVICE AND METHODS FOR QUANTIFYING ANALYTES INTRODUCTION INVITROGEN CORPORATION 2023-11-30 US disclosed
US-11635383-B2 Device and methods for quantifying analytes introduction INVITROGEN CORPORATION 2023-04-25 US disclosed
US-20070092920-A1 Serum Prolactin Binding Protein in Epithelial Carcinoma Life Technologies Corporation 2007-04-26 US disclosed
WO-2006108095-A9 SERUM BIOMARKER FOR DISEASE AND METHODS OF USING SAME UNIV MARYLAND (US) 2006-11-23 WO disclosed
WO-2006110748-A2 RESPONSE GENE TO COMPLEMENT 32 (RGC-32) IN DISEASE THE UNIVERSITY OF MARYLAND, BALTIMORE (US) 2006-10-19 WO disclosed
WO-2006108095-A2 SERUM BIOMARKER FOR DISEASE AND METHODS OF USING SAME THE UNIVERSITY OF MARYLAND, BALTIMORE (US) 2006-10-12 WO disclosed
WO-2006063213-A2 SERUM AMYLOID A PROTEIN IN INFLAMMATION AND OBESITY UNIVERSITY OF MARYLAND, BALTIMORE (US) 2006-06-15 WO disclosed
WO-2006023635-A2 METHODS OF SCREENING PROTEINS BECTON, DICKINSON AND COMPANY (US) 2006-03-02 WO disclosed
US-20060040327-A1 Methods of screening proteins AMISS TERRY 2006-02-23 US disclosed
WO-2005080988-A1 BINDING PROTEINS AS BIOSENSORS BECTON, DICKINSON AND COMPANY (US) 2005-09-01 WO disclosed
US-20050014290-A1 Binding proteins as biosensors BECTON, DICKINSON AND COMPANY 2005-01-20 US disclosed