Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016009 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7011317 | 0.78 | CHRNB2 (0.33) | ALDH1A1 | |
| SCHEMBL1963688 | 0.74 | TAAR1 (0.47) | LMNAL3MBTL1 | |
| SCHEMBL7007927 | 0.71 | HTR1D (0.57) | LMNA | |
| SCHEMBL7008008 | 0.71 | CYP2A6 (0.41) | ALDH1A1 | |
| SCHEMBL7007904 | 0.70 | KDM1A (0.44) | LMNAL3MBTL1GAAMAPT | |
| SCHEMBL7009960 | 0.70 | GAA (0.38) | ALDH1A1LMNAL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL19787572 | 0.70 | — | — | |
| SCHEMBL7009355 | 0.69 | HTR1D (0.47) | LMNA | |
| SCHEMBL7010617 | 0.69 | LMNA (0.37) | ALDH1A1LMNAL3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280793-A2 | CYCLIC AMIDINE COMPOUNDS AND THEIR USE AS ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUNTORY LIMITED (JP) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001081334-A2 | CYCLIC AMIDINE COMPOUNDS AND THEIR USE AS ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUNTORY LIMITED (JP) | 2001-11-01 | — | — | WO | disclosed |