Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC26A6 | Q9BXS9 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | PDE6A | P16499 | 1/20 | 0.40 |
| ▸ | PDE6G | P18545 | 1/20 | 0.40 |
| ▸ | PDE6B | P35913 | 1/20 | 0.40 |
| ▸ | PDE6C | P51160 | 1/20 | 0.40 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010996 | 0.92 | KDM4E (0.42) | KDM4EALDH1A1PDE5APGK1 | |
| SCHEMBL7018641 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL7015902 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL7015318 | 0.79 | ALDH1A1 (0.48) | KDM4EALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL7008203 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1KMT2ALMNAPDE5A | |
| SCHEMBL7017308 | 0.79 | PRKCI (0.50) | KDM4EALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL5130031 | 0.78 | SMN1; SMN2 (0.46) | KDM4EALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL7016074 | 0.78 | MEN1 (0.47) | KDM4EALDH1A1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7016466 | 0.76 | PDE5A (0.51) | KDM4EALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL5813077 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329454-A1 | THIENOPYRIMIDINE COMPOUNDS AND THEIR SALTS AND PROCESS FOR PREPARATION OF BOTH | NIPPON SODA CO., LTD. (JP) | 2003-07-23 | — | — | EP | disclosed |