Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 8/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009909 | 0.92 | KDM4E (0.50) | KDM4EALDH1A1PDE5APGK1 | |
| SCHEMBL7008203 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1PDE5APDE10AMAPT | |
| SCHEMBL7015902 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1PDE5APGK1PDE4B | |
| SCHEMBL7015318 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1PDE5APDE10APGK1 | |
| SCHEMBL7017308 | 0.80 | PRKCI (0.50) | KDM4EALDH1A1PDE5APDE10AMAPT | |
| SCHEMBL5130031 | 0.80 | SMN1; SMN2 (0.46) | KDM4EALDH1A1PDE5APGK1PDE4B | |
| SCHEMBL7018641 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1PDE5APGK1MAPT | |
| SCHEMBL7016466 | 0.77 | PDE5A (0.51) | KDM4EALDH1A1PDE5APGK1PDE4B | |
| SCHEMBL5813077 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1PDE5APGK1PDE4B | |
| SCHEMBL5127640 | 0.77 | PDE5A (0.46) | KDM4EALDH1A1PDE5APGK1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329454-A1 | THIENOPYRIMIDINE COMPOUNDS AND THEIR SALTS AND PROCESS FOR PREPARATION OF BOTH | NIPPON SODA CO., LTD. (JP) | 2003-07-23 | — | — | EP | disclosed |