Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 6/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010716 | 0.90 | HPGD (0.45) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7012913 | 0.86 | KDM4E (0.44) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7008423 | 0.86 | KDM4E (0.44) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7498452 | 0.85 | TOP2A (0.47) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7011168 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7013315 | 0.85 | TOP2A (0.61) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7012172 | 0.85 | TOP2A (0.52) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7006784 | 0.85 | TOP2A (0.46) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7007516 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7008300 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |