Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 9/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.46 |
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005348 | 0.90 | HPGD (0.41) | TOP2ATOP2BDPP4KDM4ELMNA | |
| SCHEMBL7010564 | 0.86 | TOP2A (0.50) | TOP2ATOP2BDPP4KDM4ELMNA | |
| SCHEMBL7010053 | 0.85 | ALDH1A1 (0.50) | TOP2ATOP2BKDM4ELMNAHSD17B10 | |
| SCHEMBL7098456 | 0.84 | LMNA (0.49) | KDM4ELMNAHSD17B10ALDH1A1HTT | |
| SCHEMBL7006571 | 0.84 | TOP2A (0.51) | TOP2ATOP2BKDM4ELMNAALDH1A1 | |
| SCHEMBL7013315 | 0.84 | TOP2A (0.61) | TOP2ATOP2BKDM4ELMNAALDH1A1 | |
| SCHEMBL7012172 | 0.84 | TOP2A (0.52) | TOP2ATOP2BKDM4ELMNAALDH1A1 | |
| SCHEMBL27445406 | 0.82 | TOP2A (0.50) | TOP2ATOP2BDPP4KDM4ELMNA | |
| SCHEMBL7498452 | 0.82 | TOP2A (0.47) | TOP2ATOP2BKDM4ELMNAALDH1A1 | |
| SCHEMBL7007624 | 0.82 | TOP2A (0.49) | TOP2ATOP2BKDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |