Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001371 | 0.78 | BRD4 (0.45) | BRD4DAO | |
| SCHEMBL7007358 | 0.77 | CREBBP (0.39) | BRD4CREBBPACSS2 | |
| SCHEMBL7005666 | 0.76 | DAO (0.41) | BRD4AKR1C3AKR1C2DAO | |
| SCHEMBL7006748 | 0.75 | BRD4 (0.45) | BRD4 | |
| SCHEMBL7005550 | 0.75 | CHEK1 (0.45) | BRD4DAO | |
| SCHEMBL7002739 | 0.75 | GRIA1 (0.39) | BRD4DAO | |
| SCHEMBL7004919 | 0.75 | MEN1 (0.42) | BRD4 | |
| SCHEMBL4751214 | 0.73 | PARP1 (0.41) | BRD4DAO | |
| SCHEMBL7007056 | 0.69 | CES1 (0.38) | DAO | |
| SCHEMBL2177417 | 0.66 | CYP2A6 (0.51) | BRD4AKR1C3AKR1C2ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |