Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001371 | 0.81 | BRD4 (0.45) | DAOBRD4CYP1A2CYP2A6PARP1 | |
| SCHEMBL7005550 | 0.78 | CHEK1 (0.45) | DAOBRD4CYP1A2ALDH1A1 | |
| SCHEMBL7006748 | 0.78 | BRD4 (0.45) | BRD4CYP2A6TYMS | |
| SCHEMBL7006777 | 0.77 | HTR7 (0.39) | DAOBRD4CYP1A2CYP2A6TYMS | |
| SCHEMBL7010349 | 0.76 | BRD4 (0.43) | DAOBRD4AKR1C3AKR1C2 | |
| SCHEMBL4751214 | 0.75 | PARP1 (0.41) | DAOBRD4PARP1ALDH1A1LMNA | |
| SCHEMBL7007056 | 0.74 | CES1 (0.38) | DAOL3MBTL1PLA2G10PLA2G2A | |
| SCHEMBL7006207 | 0.73 | GRIA1 (0.41) | DAOCYP1A2PARP1LMNAMAPT | |
| SCHEMBL7003213 | 0.73 | NSD2 (0.50) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL13266976 | 0.70 | TYMS (0.49) | DAOCYP1A2CYP2A6TYMSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |