Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31619130 | 0.77 | AHR (0.42) | CRBNMMP2 | |
| SCHEMBL6099018 | 0.68 | NPC1 (0.45) | CRBN | |
| SCHEMBL12291860 | 0.67 | IDO1 (0.37) | MAP2K1CRBNTLK2PARP1MMP2 | |
| SCHEMBL2438190 | 0.67 | PDE3B (0.39) | — | |
| SCHEMBL17160841 | 0.64 | MAOA (0.43) | — | |
| SCHEMBL1816980 | 0.64 | AHR (0.63) | — | |
| SCHEMBL3276747 | 0.62 | TDP2 (0.47) | MAP2K1PARP1 | |
| SCHEMBL18013284 | 0.62 | — | — | |
| SCHEMBL8620213 | 0.61 | ANPEP (0.32) | — | |
| SCHEMBL10969256 | 0.60 | LRRK2 (0.54) | MAP2K1TLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192153-B1 | METHOD FOR THE ENANTIOMER SEPARATION OF CIS-8-BENZYL-7,9-DIOXO-2,8-DIAZABICYCLO 4.3.0]NONANE | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1192153-B1 | METHOD FOR THE ENANTIOMER SEPARATION OF CIS-8-BENZYL-7,9-DIOXO-2,8-DIAZABICYCLO 4.3.0]NONANE | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-6566523-B1 | Reacting mixtures of enantiomers with (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid (or its hydrates) to form salts | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| US-6566523-B1 | Reacting mixtures of enantiomers with (-)-2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid (or its hydrates) to form salts | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| EP-1192153-A2 | METHOD FOR THE ENANTIOMER SEPARATION OF CIS-8-BENZYL-7,9-DIOXO-2,8-DIAZABICYCLO 4.3.0]NONANE | Bayer Aktiengesellschaft (DE) | 2002-04-03 | — | — | EP | disclosed |
| EP-1192153-A2 | METHOD FOR THE ENANTIOMER SEPARATION OF CIS-8-BENZYL-7,9-DIOXO-2,8-DIAZABICYCLO 4.3.0]NONANE | Bayer Aktiengesellschaft (DE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076996-A3 | METHOD FOR THE ENANTIOMER SEPARATION OF CIS-8-BENZYL-7,9-DIOXO-2,8-DIAZABICYCLO[4.3.0]NONANE | BAYER AG (DE) | 2001-04-12 | — | — | WO | disclosed |
| WO-2000076996-A2 | METHOD FOR THE ENANTIOMER SEPARATION OF CIS-8-BENZYL-7,9-DIOXO-2,8-DIAZABICYCLO[4.3.0]NONANE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000076996-A2 | METHOD FOR THE ENANTIOMER SEPARATION OF CIS-8-BENZYL-7,9-DIOXO-2,8-DIAZABICYCLO[4.3.0]NONANE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-21 | — | — | WO | disclosed |