Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3768476 | 0.71 | PARP1 (0.43) | GRM4 | |
| SCHEMBL29506231 | 0.70 | — | — | |
| SCHEMBL8821 | 0.70 | — | — | |
| Formamide SCHEMBL28262825 | 0.69 | DYRK1A (0.39) | — | |
| SCHEMBL4222803 | 0.68 | DYRK1A (0.45) | — | |
| Ammonia Solution, Strong SCHEMBL28492555 | 0.68 | DYRK1A (0.45) | — | |
| Iodide SCHEMBL1296857 | 0.68 | DYRK1A (0.45) | — | |
| Hydrochloric Acid SCHEMBL18284548 | 0.68 | DYRK1A (0.45) | — | |
| Bromide SCHEMBL26621962 | 0.68 | DYRK1A (0.45) | — | |
| Phosphine SCHEMBL27502321 | 0.68 | DYRK1A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | claimed |
| US-10364226-B2 | Pyridazinone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2019-07-30 | — | — | US | disclosed |
| EP-3030549-B1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | ALIOS BIOPHARMA INC (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20160221963-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | Janssen Pharmaceuticals, Inc. | 2016-08-04 | — | — | US | disclosed |
| EP-3030549-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | Alios Biopharma, Inc. (US) | 2016-06-15 | — | — | EP | disclosed |
| WO-2015038660-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | ALIOS BIOPHARMA, INC. (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2015038449-A1 | COATING COMPOSITIONS AND METHODS FOR THEIR USE | BAYER MATERIALSCIENCE LLC (US) | 2015-03-19 | — | — | WO | disclosed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221963-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | PDXK, PNPO, PLPBP | GRM4 2263/4885MKNK1 456/4885 |
| US-10364226-B2 | Pyridazinone compounds and uses thereof | PDXK, PNPO, PLPBP | GRM4 2263/4885MKNK1 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.