Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31724329 | 0.81 | NAMPT (0.48) | LMNAMAPK1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4986629 | 0.80 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL14393514 | 0.79 | OPRM1 (0.63) | POLBMAPK1ALDH1A1HTTKMT2A | |
| SCHEMBL13675427 | 0.79 | KDM4E (0.51) | LMNAKDM4EL3MBTL1SMN1; SMN2CYP2C9 | |
| SCHEMBL13673895 | 0.76 | KDM4E (0.49) | LMNAKDM4EL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL6954924 | 0.76 | KCNA5 (0.56) | LMNAALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL25564133 | 0.76 | KCNA5 (0.54) | ITGB3ITGAVLMNAKDM4EHTT | |
| SCHEMBL2298713 | 0.76 | KCNA5 (0.56) | LMNAALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL28442669 | 0.76 | SMN1; SMN2 (0.46) | ITGB3ITGAVLMNAALDH1A1HTT | |
| SCHEMBL21523087 | 0.75 | EPHX2 (0.65) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280793-A2 | CYCLIC AMIDINE COMPOUNDS AND THEIR USE AS ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUNTORY LIMITED (JP) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001081334-A2 | CYCLIC AMIDINE COMPOUNDS AND THEIR USE AS ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUNTORY LIMITED (JP) | 2001-11-01 | — | — | WO | disclosed |