Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673895 | 0.83 | KDM4E (0.49) | KDM4ESLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL29669002 | 0.79 | SLC6A4 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL1037866 | 0.79 | SLC6A4 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL3465672 | 0.79 | SLC6A4 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL6855637 | 0.79 | SLC6A4 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL7010733 | 0.79 | POLB (0.48) | KDM4ECYP3A4CYP2D6SMN1; SMN2CYP2C9 | |
| SCHEMBL9129451 | 0.79 | SLC6A3 (0.53) | KDM4ESLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL4048311 | 0.79 | SLC6A3 (0.55) | KDM4ESLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL6320255 | 0.79 | SLC6A3 (0.55) | KDM4ESLC6A2SLC6A4SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL9073846 | 0.78 | SLC6A4 (0.47) | KDM4ESLC6A2SLC6A4SLC6A3CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | PKD2, PKD1, AADAT | KDM4E 757/4885SLC6A2 2096/4885SLC6A4 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.