Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820684 | 0.90 | MTNR1A (0.41) | MTNR1ASLC6A4DRD2FFAR1 | |
| SCHEMBL7014782 | 0.81 | MTNR1A (0.41) | MTNR1ASLC6A4DRD2FFAR1HTR5A | |
| SCHEMBL7011548 | 0.80 | MTNR1A (0.43) | MTNR1ASLC6A4DRD2HTR5ANPC1 | |
| SCHEMBL7228652 | 0.80 | MTNR1A (0.43) | MTNR1ASLC6A4DRD2HTR5ANPC1 | |
| SCHEMBL7006204 | 0.79 | MTNR1A (0.40) | MTNR1ASLC6A4DRD2FFAR1HTR5A | |
| SCHEMBL8819825 | 0.78 | SLC6A4 (0.41) | MTNR1ASLC6A4DRD2 | |
| SCHEMBL10224643 | 0.78 | MTNR1A (0.62) | MTNR1AHTR5ACYP2A6MTNR1B | |
| SCHEMBL7237119 | 0.76 | MTNR1A (0.40) | MTNR1ASLC6A4CYP2A6 | |
| SCHEMBL7237123 | 0.76 | MTNR1A (0.40) | MTNR1ASLC6A4CYP2A6 | |
| SCHEMBL9613202 | 0.73 | MTNR1A (0.45) | MTNR1ASLC6A4NPC1RAB9ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |