Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820684 | 0.89 | MTNR1A (0.41) | SLC6A4DRD2HTR6HTR2CHTR1A | |
| SCHEMBL7867549 | 0.85 | HTR6 (0.42) | SLC6A4DRD2HTR6HTR1ASLC6A2 | |
| SCHEMBL7468044 | 0.78 | SLC6A2 (0.44) | SLC6A4HTR6HTR1ASLC6A2SLC6A3 | |
| SCHEMBL7010863 | 0.78 | MTNR1A (0.46) | SLC6A4DRD2MTNR1A | |
| Hydrochloric Acid SCHEMBL1673605 | 0.77 | SLC6A2 (0.43) | SLC6A4HTR6HTR2CHTR1ASLC6A2 | |
| SCHEMBL22860683 | 0.75 | SLC6A4 (0.45) | SLC6A4DRD2HTR6HTR2CHTR1A | |
| SCHEMBL7870932 | 0.75 | HTR6 (0.42) | SLC6A4DRD2HTR6MTNR1A | |
| SCHEMBL13201190 | 0.75 | HTR2C (0.49) | SLC6A4HTR6HTR2CHTR1ASLC6A2 | |
| SCHEMBL4676658 | 0.74 | SLC6A4 (0.55) | SLC6A4DRD2HTR6HTR2CHTR1A | |
| SCHEMBL29868908 | 0.74 | SLC6A4 (0.55) | SLC6A4DRD2HTR6HTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047302-A1 | INHIBITION OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |