Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009483 | 0.94 | HPGD (0.43) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7008348 | 0.91 | ALDH1A1 (0.47) | HPGDKMT2AMEN1MAPTTP53 | |
| SCHEMBL7008688 | 0.89 | ADRB2 (0.45) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL8323507 | 0.88 | KMT2A (0.42) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7008238 | 0.88 | KMT2A (0.42) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7008233 | 0.87 | HPGD (0.38) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7012150 | 0.84 | KDM4E (0.46) | HPGDKMT2AMEN1MAPTTP53 | |
| SCHEMBL7010320 | 0.84 | TOP2A (0.49) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7008129 | 0.83 | ADRB2 (0.44) | HPGDKMT2AMEN1MAPTTHRB | |
| SCHEMBL7010122 | 0.82 | ADRB2 (0.43) | HPGDKMT2AMEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |