Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012150 | 0.93 | KDM4E (0.46) | ALDH1A1HPGDHTTKDM4EPOLB | |
| SCHEMBL7010993 | 0.91 | HPGD (0.48) | ALDH1A1HPGDHTTKDM4EGAA | |
| SCHEMBL7012172 | 0.86 | TOP2A (0.52) | ALDH1A1HTTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL7010134 | 0.85 | DRD3 (0.48) | ALDH1A1HPGDHTTKDM4EPOLB | |
| SCHEMBL7009483 | 0.85 | HPGD (0.43) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL8322686 | 0.85 | TOP2A (0.41) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7014091 | 0.85 | TOP2A (0.41) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7009950 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HPGDHTTKDM4EPOLB | |
| SCHEMBL7013315 | 0.82 | TOP2A (0.61) | ALDH1A1HTTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL7011126 | 0.81 | CD4 (0.37) | ALDH1A1HPGDHTTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |