Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698464 | 0.93 | MEN1 (0.46) | MEN1KMT2AALDH1A1LMNAEPHX2 | |
| SCHEMBL4294627 | 0.89 | MEN1 (0.46) | MEN1KMT2AALDH1A1LMNAEPHX2 | |
| SCHEMBL708425 | 0.88 | MEN1 (0.45) | MEN1KMT2AALDH1A1LMNAEPHX2 | |
| SCHEMBL3441805 | 0.86 | MEN1 (0.43) | MEN1KMT2AALDH1A1LMNAEPHX2 | |
| SCHEMBL3441783 | 0.86 | TACR1 (0.44) | MEN1KMT2AALDH1A1LMNAEPHX2 | |
| SCHEMBL700251 | 0.84 | CCR5 (0.57) | LMNACCR5 | |
| SCHEMBL701189 | 0.82 | MEN1 (0.45) | MEN1KMT2AALDH1A1LMNAEPHX2 | |
| SCHEMBL10246542 | 0.81 | CHRNB2 (0.42) | ALDH1A1CCR1CHRNA7HRH3CHRNB2 | |
| SCHEMBL709333 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1LMNAEPHX2 | |
| SCHEMBL3441634 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264407-A1 | Substituted Sulfonamide Compounds | CNR1, SUCNR1, OPRL1 | MEN1 3536/4885KMT2A 3631/4885ALDH1A1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.