Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.36 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 6/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699942 | 0.86 | HTR7 (0.36) | HTR7HTR1A | |
| SCHEMBL700842 | 0.83 | HTR7 (0.51) | DRD2DRD3HTR7HTR1DHTR2B | |
| SCHEMBL3441590 | 0.82 | NPY1R (0.35) | CCR1NPY1RDRD2DRD3CCR5 | |
| SCHEMBL701483 | 0.81 | HTR7 (0.40) | CCR1DRD2DRD3HTR7HTR1D | |
| SCHEMBL700048 | 0.80 | ALDH1A1 (0.37) | DRD2DRD3HTR7 | |
| SCHEMBL4297415 | 0.79 | NPY1R (0.33) | CCR1NPY1RDRD2DRD3CCR5 | |
| SCHEMBL4299091 | 0.78 | ALDH1A1 (0.35) | CCR1NPY1RDRD2DRD3HTR7 | |
| SCHEMBL701428 | 0.77 | HCRTR1 (0.35) | HTR7 | |
| SCHEMBL704619 | 0.76 | BDKRB1 (0.40) | — | |
| SCHEMBL3409743 | 0.76 | CCR1 (0.34) | CCR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | claimed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | claimed |
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264407-A1 | Substituted Sulfonamide Compounds | CNR1, SUCNR1, OPRL1 | CCR1 1126/4885NPY1R 109/4885PAX8 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.