Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808670 | 0.83 | GAA (0.66) | L3MBTL1ALDH1A1HTTSMN1; SMN2PPARG | |
| SCHEMBL720990 | 0.83 | MAPT (0.57) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL14901534 | 0.82 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1HTTPPARGMAPT | |
| SCHEMBL5290227 | 0.81 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL7016246 | 0.81 | ELANE (0.62) | L3MBTL1ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL15496878 | 0.81 | RARB (0.57) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10030181 | 0.80 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL23929839 | 0.80 | GSK3B (0.57) | L3MBTL1ALDH1A1MAPTGAARAB9A | |
| SCHEMBL15084279 | 0.80 | GAA (0.66) | L3MBTL1HTTGAAPPARA | |
| SCHEMBL2696204 | 0.79 | L3MBTL1 (0.72) | L3MBTL1ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |