Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015033 | 0.82 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL7013025 | 0.79 | AGTR1 (0.46) | AGTR1PPARG | |
| SCHEMBL13070295 | 0.78 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL2775196 | 0.77 | AGTR1 (0.74) | AGTR1 | |
| SCHEMBL2774345 | 0.76 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL2779116 | 0.76 | AGTR1 (0.56) | AGTR1PPARG | |
| SCHEMBL2773642 | 0.76 | AGTR1 (0.73) | AGTR1PPARG | |
| SCHEMBL7013031 | 0.75 | FABP4 (0.43) | AGTR1PPARG | |
| SCHEMBL3976423 | 0.75 | PPARG (0.41) | AGTR1PPARG | |
| SCHEMBL2774436 | 0.75 | AGTR1 (0.62) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-5389641-A | Fused heterocyclic compounds, having angiotensin II antagonistic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0518033-A1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |